Evaluation of Antibacterial Activity of some Medicinal Plants Extracts Commonly Used in Algerian Traditional Medicine against some Pathogenic Bacteria
Mohamed Senouci Bereksi, Hafida Hassaïne , Chahrazed Bekhechi , Djamel Eddine Abdelouahid
Original Article, Pharmacogn J. 2018; 10(3):507-512.
DOI : 10.5530/pj.2018.3.83
ABSTRACT
Introduction: The objective of this study was to evaluate the antibacterial activity of hydromethanolic
extracts of Berberis vulgaris, Cassia angustifolia, Cinnamomum cassia, Cistus
monspeliensis, Nigella sativa, Punica granatum, Rhus tripartata, Withania frutescens and
Zingiber officinale against different Gram-positive and Gram-negative reference bacterial
strains. Methods: The evaluation of antibacterial activity for different extracts of each plant
was carried out using the disc diffusion method and determination of minimum inhibitory
concentration (MIC). Results: The plant extracts showed zone of inhibition ranging from 06.0
to 23.0 mm against one or more tested bacteria, and their efficacy in terms of MICs where
ranged from 0.1 to 12.8 mg/mL. The Refluxed and Macerated extracts of these plants have
shown relatively similar results in terms of diameters of inhibition and MICs. The extracts of
B. vulgaris, C. monspeliensis and P. granatum demonstrated relatively high activity as
compared to the other plant extracts mainly against S. aureus, E. faecalis and E. cloacae.
Conclusion: Findings of this study indicate that hydromethanolic extracts of these plants
have antibacterial activity against the different tested bacterial strains. This activity supports
their use in treatment of infections caused by such resistant bacteria.
Key words: Medicinal plants, Hydromethanolic extracts, Antibacterial activity, Inhibition
zones, MICs, Bacterial resistance.
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